أرقك يبدأ من أمعائك؟ خريطة ميكروبية جديدة تقود العلاج

A recent study outlines a complex relationship between the gut microbiome and insomnia; it identified 14 bacterial groups associated with an increased risk of developing the condition, compared to 8 groups linked to a decreased risk. Most importantly, the analysis showed that insomnia itself alters the balance of the microbiome, weakening some species by up to 79% and increasing others by more than 4 times, suggesting a cycle of mutual influence that may sustain the disorder. These findings open a new therapeutic avenue towards microbiome-modifying interventions—through probiotics or personalized nutrition—rather than relying entirely on sedative medications with side effects. They also prompt a reconsideration of insomnia diagnosis as a disorder with a metabolic-inflammatory dimension related to the gut, rather than merely an isolated sleep problem. Although the results do not establish definitive causality, the strength and consistency of the associations support future clinical trials targeting the "risk-raising" bacteria and enhancing the "protective" ones, which could transform insomnia treatment from temporary relief to a deeper biological correction.